Kaposi's sarcoma and coexistent giant follicular lymphoblastoma.

Various reports of coexistent Kaposi's sarcoma and malignant lymphomas have appeared in the literature." This combination occurs with a greater frequency than would be predicted on the basis of random association. The two diseases may appear both as anatomically separate lesions and as a mixture of the two lesions in the same specimen of skin or lymph node, suggesting that there may be a transition from one type of tumor into the other, or that they may have a common precursor, such as the reticulum cell.' Reports of giant follicular lymphoblastoma in association with Kaposi's sarcoma have been rare, only two cases having been previously described in the literature, by Pack and Davis in 1954.2 A patient has been encountered who demonstrates this interesting association. He first developed typical clinical and histologic features of giant follicular lymphoblastoma, and subsequently developed widespread cutaneous and visceral lesions of Kaposi's sarcoma. This case is of particular interest because the cause of death was the rapidly progressive visceral Kaposi's sarcoma rather than the malignant lymphoma.